Article provides a historical overview of the health conditions among the five large tribes of Indian Territory from 1830 to the Civil War. Bernice Norman Crockett explores how epidemics and liquor trade impacted the Cherokee, Chickasaw, Choctaw, Seminole, and Creek tribes, and the medical help that was available via missionaries.

Notes and Documents section for Volume 35, Number 1, Spring 1957. It includes a note about a new booklet published by the OHS, a document about the settlement of No Man's Land, a reprint of notes about the creation of a bridge across the Red River, a document about the flags raised in Oklahoma Territory, and a detailed set of instructions for the route of the Washington Irving Trail tour written by George H. Shirk.

This section includes the minutes of the quarterly meeting of the Board of Directors of the Oklahoma Historical Society held on January 24, 1957.

Article discusses the history of Cimarron Territory, also known as "No Man's Land" and the Oklahoma Panhandle, while describing the origin of the seal of Cimarron Territory that is displayed on the cover of this issue of The Chronicles.

Article discusses the history of Shade's Will on Zach Cain's Ranch, its founding by J. U. Shade and H. B. Fore, its importance as a stop for water in the cattle trade, and how it was developed in conjunction with Shade's Well Inn on the ranch.

Article discusses the lives of the pioneer couple Dr. Richard Moore Crain and his wife, who was Miss Anna Rebecca Neal before marriage. Carolyn Thomas Foreman discusses the difficulties they faced on the frontier, Anna's work as a schoolteacher, and Dr. Cain's work with the various tribes they lived among.

Article discusses the creation of the Butterfield Overland Mail Route and its development. Muriel H. Wright explores how mail was transported by railroad and stagecoaches across the route, and the events that impacted the route's success.

Article includes the memoires of Kittie M. Harvey, a pioneer woman who moved to Oklahoma Territory with her family and became a music teacher and helped run the small post office in Chandler. Harvey discusses life there and in Oklahoma City, and the people she and her husband Will Harvey interacted with.

Article provides a biographical sketch of the life and career of Albert Clarence Hunt, Justice of the Supreme Court of Oklahoma. Judge N. B. Johnson discusses the leadership positions the justice held, as well as the organizations he was a part of.

Article discusses the history of No Man's Land, or old Beaver County, its initial land system after being claimed by Spain, various contracts over land use, the founding of the Santa Fe Trail, and the area's time as Cimarron Territory. This article is a reprint of the original, which was contained in the first issue of the Chronicles in 1921.